GC-MS ANALYSIS OF CURCUMA ZEDOARIA TUBER EXTRACTS AND ITS ANTIBACTERIAL ACTIVITY

This study investigates the presence of bioactive compounds present in the tubers of Curcuma zedoaria using GC-MS analysis. Different compounds, including alkaloids, tannins, flavonoids, and proteins, were identified using the preliminary phytochemical screening for aqueous, ethanol and methanol extracts. The present study reports the antimicrobial activity analysis using aqueous, ethanol and methanol extracts. The results show that the ethanol and methanol extracts showed relatively enhanced results. The extracts were subjected to GC-MS analysis, and antibacterial properties for the extracts were analyzed. Bioactive compounds such as 1,2 cyclopentanedione, 2(5H)-furanone, hexadecanoic acid, succinic acid, oleic acid, pyrrolidine etc., were identified through GC-MS. These compounds exhibited various therapeutic functions such as anticancer, anti-inflammatory, and anti-microbial activity. The antibacterial assay showed a considerable zone of inhibition for the ethanolic extracts in the case of K. pneumonia and B. subtilis. Hence, these crude extracts can be used as a better and alternative source, which can be used in herbal medicines. The study concluded that C. zedoaria tuber contains various bioactive compounds. Therefore, this tuber can be considered of phytopharmaceutical importance.