GENERAL CONSIDERATION OF GUILLIAIN BARRE SYNDROMEAbstract
Guillain-Barré syndrome is a rare but important disease that can lead to life threatening respiratory failure. This review summarises the verified consideration of Guillain-Barré syndrome (GBS) which are thought to be caused by direct autoimmune attack on peripheral nerves. Aim- Nerve conduction study helps differentiate the heterogeneous subtypes of GBS. Patients exhibit a progressive paralysis that reaches a plateau phase. Treatment and Result- Treatment with both intravenous immunoglobulin and plasma exchange reduces the time taken for recovery to occur, although mortality remains around 8%, with about 20% of patients remaining disabled. Though no significant differences were found between patients with Guillain Barre syndrome treated with plasma exchange and patients treated with intravenous immune globulins either alone or in combination with high dose methylprednisolone. Conclusion- It can be concluded that tentative and the gap in current research should not be interpreted as proof that multidisciplinary care is ineffective. Further research is needed into appropriate study designs; outcome measurement; caregiver needs; and the evaluation of optimal settings, type, intensity or frequency and cost-effectiveness of multidisciplinary care in the Guillain-Barré syndrome population.
Zeel A. Gandhi, Brijal A. Maisuria, Rajesh G. Patel and Bhoomi Arora*
Institute of Clinical Research India, Ahmedabad, Gujarat, India
11 July, 2012
06 August, 2012
21 October, 2012