GREEN SYNTHESIZED GOLD NANOPARTICLE: A NOVEL APPROACH TOWARDS BIOMEDICAL AND PHARMACEUTICAL APPLICATIONSAbstract
Green synthesized gold nanoparticle is one of the most promising drug delivery approaches with biocompatibility and biodiversity. Various plant sources such as Aegle marmelos, Eugenia jambolana, Soursop, Persea Americana, Terminalia chebula, Aloe arborescens, Musa paradisiacal, Alternanthera philoxeroides, Cissus quadrangularis, Sterculia acuminate, Garciniaindica choissy, Eucalyptus globulus, Rosmarinus officinalis, Punica granatum, Pistacia atlantica, Pistacia integerrima, Juglans regia, Curcumae kwangsiensis; fungal sources as Pleurotus cornucopiae var. citrinopileatus, Cladosporium cladosporioides; other microbial sources as Magnusiomyces ingens LH-F1, Micrococcus yunnanensis, Padina tetrastromatica are used to develop biocompatible gold nanoparticle with veritable diversified particle size and applicability profile as anticancer (especially against breast cancer, liver cancer, ovarian cancer and lung cancer), antibacterial agent, photo luminescent, heavy metal sensor, etc. If biogenic sources are composed of a large number of hydroxyl and carboxylic acid groups, it can behave as reducing agents to develop gold nanoparticles with immense biomedical and pharmaceutical applications. This novel approach and data are very much encouraging and may be considered as one platform for searching all the important green synthesized gold nanoparticles and might be an index for evaluating drug activities.
Dilipkumar Pal * and Supriyo Saha
Department of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur, Chhattisgarh, India.
04 August 2020
11 February 2021
24 May 2021
01 October 2021