HISTOPATHOLOGICAL ANALYSIS OF ENDOMETRIAL TISSUE IN CASES OF ABNORMAL UTERINE BLEEDING – A 2-YEAR RETROSPECTIVE STUDY IN A TERTIARY CARE HOSPITAL

Background: Abnormal uterine bleeding (AUB) is one of the most common gynaecological complaints and a major indication for endometrial sampling. Histopathological evaluation remains the gold standard for identifying functional, organic, premalignant, and malignant lesions. Objective: To analyse the spectrum of histopathological patterns of endometrium in women presenting with AUB and to assess the association of age with significant endometrial pathology. Materials and Methods: This retrospective study included all endometrial biopsy and hysterectomy specimens received for AUB over a period of two years in a tertiary care hospital. Histopathological findings were categorized and correlated with age groups. Statistical analysis included chi-square test and binary logistic regression. Results: The most common finding was proliferative endometrium followed by pregnancy-related changes and secretory endometrium. Hyperplasia and carcinoma were predominantly seen in women above 40 years. Conclusion: Endometrial histopathology shows a strong age-dependent distribution. Increasing age is a significant predictor of organic and premalignant/malignant endometrial pathology, reinforcing the importance of routine histopathological evaluation in women with AUB.