HPLC ANALYSIS OF CEPHALOSPORINS AND STUDY OF DIFFERENT ANALYTICAL PARAMETERSAbstract
Cephalosporins are the most important type of antibiotics used vary widely. Analysis of these antibiotics is challenge because of their sensitivity and instability to different conditions. The present review is extended to find out different HPLC methods used for analysis for cephalosporins in formulations and biological fluids. The chromatographic conditions used for the analysis as well as analytical parameters study carried out with different experimental conditions and different combinations. During the study analytical parameters studied such as range, linearity, precision, accuracy, LOD, LOQ etc. The focus of study of analysis of cephalosporin in formulation and biological fluid are useful for the determination of various cephalosporin for budding researchers.
P. N. Patil* and S. Jacob
Department of Chemistry, Bharati Vidyapeeth’s College of Engineering, Near Chitranagari, Kolhapur, Maharashtra, India
10 August, 2011
04 November, 2011
22 December, 2011