HUMAN RED BLOOD CELL MEMBRANE STABILITY TESTING FOR THE ESTIMATION OF ANTI-INFLAMMATORY ACTIVITY OF METHANOLIC EXTRACT OF MILLETTIA PACHYCARPA BENTH LEAVESAbstract
The present study is carried out with the methanolic extract of leaves of Millettia pachycarpa benth. Traditional use of it inspired us to investigate the blood corpuscular protective power of this plant as it used as blood tonic in Chinese traditional medicine. By the phytochemical screening we have both flavonoids and steroids. There’s also alkaloids are found which have extensive physiologic action embodying analgesic activity. This investigation is made following the most simple, reliable and less time consuming method. As the human red blood corpuscular membrane is similar to lysosomal membranes that influence inflammatory process. Result obtained using methanolic extract of M. pachycarpa have better acceptance as it shows good response in inhibiting hemolysis (34.30%) at highest concentration and these investigation surely stimulate further screening and isolation process.
Amin Chowdhury, Abdullah Al Mamun, Shadman Rahman, Shofiul Azam*, Kishower Shams and Abdullah Jainul
Department of Pharmacy, International Islamic University Chittagong, 154/A, College road, Chittagong-4203, Bangladesh
13 July, 2013
20 August, 2013
17 November, 2013
01 December 2013