HYPOGLYCEMIC ACTIVITY OF PUTRANJIVA ROXBURGHII WALL. IN ALLOXAN INDUCED DIABETIC RATSAbstract
Diabetes mellitus is the most common endocrine disorder that impairs glucose homeostasis resulting in severe diabetic complicationsincluding retinopathy, angiopathy, nephropathy, neuropathy and causing neurological disorders due to perturbation in utilization of glucose. In the present study diabetes was induced in albino rat models with alloxan monohydrate. Putranjiva roxburghii Wall. has been claimed to possess antidiabetic properties by many investigators. The present study was undertaken to screen the hypoglycemic activity of ethanol extracts of leaves of Putranjiva roxburghii. The results showed that it has significant antihyperglycemic effect in experimental model of diabetes mellitus.
Amit Varma*, S. K. Jain and Shashi Alok
Department of Pharmacognosy, Institute of Pharmacy, Bundelkhand University, Jhansi, (U.P.), India
29 August, 2010
21 November, 2010
27 December, 2010
01 January, 2011