IDENTIFICATION OF AEROTOLERENCE GENE BATA AND BATB IN SUBGINGIVAL MICROFLORA: AGGREGATIBACTER ACTINOMYCETEMCOMITANS, TANNERELLA FORSYTHIA AND PREVOTELLA INTERMEDIAAbstract
Subgingival obligate anaerobes present within the biofilm such as Porphyromonas gingivalis, Tannerella forsythia, Prevotella intermedia and Aggregati bacter actinomycetemcomitans have been implicated in the initiation and progression of periodontal disease. Recent documentation has demonstrated that P.gingivalis is capable of maintaining its viability when exposed to oxidative stress by expressing Bat A and Bat B genes of the aerotolerance operon acting as virulence factors offering protection and further disease progression in the host. The present study aims to determine the presence of bat A and bat B genes in other periodontopathogenic species viz. Aggregatibacter actinomycetemcomitans, Tannerella forsythia and Prevotella intermedia, and the degree of homology using BLAST analysis.
H. Parthsarathy, R. Gad and C. A. Jacob *
Department of Periodontology, Saveetha Dental College, Chennai, TN, India
11 August, 2015
22 October, 2015
05 December, 2015
01 February, 2016