IMPACT OF LEVOTHYROXINE SUPPLEMENT ON TRIGLYCERIDES AND VERY LOW-DENSITY LIPOPROTEINS IN HYPOTHYROID PATIENTSAbstract
Our aim is to observe the impact of Levothyroxine supplement on Triglycerides and Very- low-density lipoproteins in Hypothyroid patients. This study is to observe the incidence of Dyslipidemia condition (elevated TG’s, VLDL levels) and the impact of levothyroxine supplement on TG’s and VLDL in hypothyroidism patients. Our current study is an observational study, which involves observation of hypothyroid patients and their TSH levels, TG’s, VLDL levels. The results showed that, out of 150 patients, 65 people came under group I, and 85 people were under group II. In Group-I, patients with elevated TG’s and VLDL’s were found to be 10(15. 38%), 6(9.23%) respectively. Similarly, in Group-II, patients with elevated TG’s and VLDL̓s were found to be 46(54.11%), 38(65.51%), respectively. Finally, we conclude that treatment with levothyroxine in patients with a history of hypothyroidism above 5 years resulted in the maintenance of normal TSH levels, TG’s and VLDL levels when compared with those patients who had a history of hypothyroidism below 5 years with elevated TSH, TG’s and VLDL levels.
A. Laxmi Sowjanya, N. Divya, P. Madhu Varma and Kumaraswamy Barla *
Department of Pharmacology and Pharmacy Practice, Sir C. R. Reddy College of Pharmaceutical Sciences, Eluru, Andhra Pradesh, India.
07 September 2020
03 February 2021
23 May 2021
01 September 2021