IMPACTS OF KETOROLAC TROMETHAMINE IN TRANSDERMAL DRUG DELIVERY SYSTEMAbstract
Transdermal drug delivery system (TDDS) established itself as an integral part of novel drug delivery systems which employ a structure as a reservoir for the drugs. A number of drugs have reached the market in transdermal delivery form that has become an increasingly acceptable mode for administration of prescription and nonprescription drugs. Transdermal drug delivery system possesses many advantages over conventional modes of drug administration. Ketorolac when combined with tromethamine forms a salt (‘ketorolac tromethamine’), which has a greater aqueous solubility than ketorolac. Ketorolac tromethamine is a Nonsteroidal anti-inflammatory drug useful for short-term management of moderate to severe pain. Ketorolac tromethamine has high analgesic and anti-inflammatory potency; administered orally. The focus of this review article is to bring out different aspect related with the administration and its future impacts on human body after administration of ketorolac in transdermal drug delivery system.
Amit Kumar Jha*
Department of Pharmaceutics, School of Pharmacy, Suresh Gyan Vihar University, Jagatpura, Jaipur, Rajasthan, India
29 June, 2010
27 September, 2010
13 November, 2010
01 December, 2010