IN-SILICO TOOLS IN THE PREDICTION OF COUMARIN SCHIFF BASES AS POTENTIALLY ACTIVE COMPOUNDS: A COMPARATIVE STUDYAbstract
In the present study two subclasses of coumarin derivatives were selected 14 coumarin sulphonamides and 14 coumarin schiff bases i.e., totally 28 compounds from our earlier research work. A comparative study for two subclasses of coumarins by using various CADD (online and offline) softwares. Computational calculations and predictions of important molecular properties suggest that among the two sub classes of coumarin derivatives, coumarin Schiff bases could be further improved to provide biologically active agents.
K. N. V. C. Lakshmi *, B. Anupama, G. Yamini, M. Navyatejasree and M. Saisree
Department of Pharmaceutical Chemistry, QIS College of Pharmacy, Vengamukkapalem, Ongole, Andhra Pradesh, India.
18 February 2019
28 March 2019
17 April 2020
01 July 2020