IN VITRO ANTIBACTERIAL POTENTIAL OF GLYCOSIDIC AND AGLYCONIC CRUDE EXTRACTS OF CASSIA SIEBERIANA DC. (CESALPINIACEAE) AND KHAYA GRANDIFOLIOLA C.DC. (MELIACEAE): A COMPARATIVE SURVEY
AbstractCassia sieberiana and Khaya grandifoliola are two plants from Ivorian traditional pharmacopoeia. In this study, we have compared in vitro antibacterial potential of glycosidic and aglyconic crude extracts from both plant species against 3 reference bacterial strains (Escherichia coli ATCC 25922, Pseudomonas aeruginosa 27853, Staphylococcus aureus ATCC 25923) and 4 others clinical (Proteus mirabilis, Salmonella sp, Shigella sp, Vibrio cholerae) isolated from pathological specimen at hospital. The results have revealed on all tested bacteria, a clear antibacterial potential of aglycones compared to glycosides. Indeed, at same concentrations, total aglycones of each plant have inhibition zones more extensive than their corresponding glycosides, and their MIC are clearly lower against bacterial strains. Moreover, we note that the aglycones are active against Escherichia coli ATCC 25922 and Pseudomonas aeruginosa 27853 while when the glycosides are inactive. This suggests that in the glycoside, the sugar moiety inhibits the antibacterial action.
Article Information
9
2728-33
528
1422
English
Ijpsr
L. Traoré , B. B. Boua , N. K. Guessennd , B. A. Kadja , J. A. Mamyrbékova-Békro and Y. A. Békro *
Laboratoire de Chimie Bio Organique et de Substances Naturelles (LCBOSN), UFR-SFA, Université Nangui Abrogoua, Abidjan 02- Côte d’Ivoire, Brasil
bekro2001@yahoo.fr
03 November 2014
09 January, 2015
28 February, 2015
10.13040/IJPSR.0975-8232.6(7).2728-33
01 July, 2015
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