IN VITRO ANTICANCER ACTIVITY OF ETHYL ACETATE EXTRACT AND GREEN NANOPARTICLE SYNTHESIZED FROM CURCULIGO ORCHIOIDES GAERTN – AN ENDANGERED MEDICINAL PLANTAbstract
The present study aimed at to study the antioxidant and anticancer activity of ethyl acetate extract and nanoparticles synthesized from Curculigo orchioides. The ethyl acetate extract andnanoparticle synthesized from C. orchioides were used in various antioxidant assays such as DPPH, hydroxyl radicals, hydrogen peroxide and nitric oxide radical scavenging activities. The synthesis of silver nanoparticles was characterized by UV-Vis spectro-photometer, X-ray diffractometer (XRD) and Scanning Electron Microscope (SEM). The maximum growth inhibitory effects (66.12% and 71.28%) on MCRF-7 cell line were observed in ethyl acetate extract and nanoparticle at 80µg/ml concentration after 48 hr treatment.
T. Selvaraj and P. Agastian*
Department of Plant Biology and Biotechnology, Loyola College, Chennai, Tamil Nadu, India.
05 January, 2017
16 May, 2017
21 June, 2017
01 July, 2017