IN VITRO ANTICANCER ACTIVITY OF GMELINA ASIATICA L. LEAF AGAINST HUMAN BREAST CANCER CELL LINE (MCF-7)
AbstractThe present study was taken to prove the cytotoxic effect of ethanolic extract of Gmelina asiatica leaf on human breast cancer cell line MCF-7. The in vitro cytotoxicity was evaluated by performing MTT assay. Cell morphological characteristics were observed by using phase contrast microscope. The results demonstrated in MCF-7 cancer cell lines treated with ethanolic extract of G. asiatica leaf showed the cell death which is dose dependent. Only 8.2 % of cell viability was observed at 1000µg/ml concentration of G. asiatica leaf extract. It is concluded that the ethanolic extract of Gmelina asiatica leaf can be used for the treatment of breast cancer.
Article Information
35
2116-21
579
1443
English
IJPSR
A. R. Florence and S. Jeeva *
Department of Botany, Scott Christian College (Autonomous), Nagercoil, Tamilnadu, India
solomonjeeva@gmail.com
20 November, 2015
10 March, 2016
23 March, 2016
10.13040/IJPSR.0975-8232.7(5).2116-21
01 May 2016
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