IN-VITRO ANTIOXIDANT AND ANTIBACTERIAL ACTIVITY OF DIFFERENT EXTRACTS OF DIOSPYROS MELANOXYLON ROXB.

The present research focuses on the screening of phytochemicals from an Indian medicinal plant Diospyros melanoxylon Roxb. by both qualitative and quantitatively and biological activities. Different solvent extracts were prepared and used for this study such as hexane, chloroform, methanol, ethyl acetate and aqueous. Preliminary screening of phytochemicals revealed that the methanolic extract comprises alkaloids, carbohydrates, flavonoids, glycosides, phenols, saponins, tannins, terpenoids and triterpenoids than the other extracts. Further, in-vitro antibacterial activity was studied by well diffusion method using four different human pathogens viz. Acinetobacter baumannii, Escherichia coli, Salmonella typhi, and Staphylococcus aureus. Followed by, 3 different in-vitro antioxidant activities were performed in 5 different plant extracts. The antioxidant study revealed that the methanolic extract showed significant antioxidant activity than the others which indicate that methanol extract played an essential role in biological activities. Thus, Diospyros melanoxylon could be effectively employed as an ingredient in health or functional food to alleviate oxidative stress and related health benefits.