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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

IJPSR is indexed with Embase

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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IN- VITRO ANTIOXIDANT AND CYTOTOXIC POTENTIAL OF CALOTROPIS PROCERA (R. BR.) ROOT

Abstract

This study evaluated the in vitro antioxidant and cytotoxic potential of methanolic extract of the root of Calotropis procera (R. BR.). The Antioxidant activity of the extract was investigated by the In-vitro Anti-Oxidant activity (DDPH Scavenging activity) assays. The IC50 of the Calotropis procera studied by the above mention method was found below 100 μg/ml which indicates the potent antioxidant activity of the plant. The extract of the root of Calotropis procera also demonstrated a strong cytotoxic activity against brine shrimp nauplii with an LC50 value of 2.931 μg/ml.

Article Information

31

2132-2135

603

1146

2

English

Ijpsr

Md. Zakaria Faruki , Mithilesh Kumar Jha*, Md. Mofizur Rahman , M. B. Alam , M.E.H. Mazumder and Md. Sohel Rana

Lecturer, Department of Pharmacy, School of Health and Allied Sciences, Pokhara University, Lekhnath-12, Kaski, Nepal

05 April, 2011

10 June, 2011

09 July, 2011

http://dx.doi.org/10.13040/IJPSR.0975-8232.2(8).2132-35

01 August, 2011

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