IN- VITRO ANTIOXIDANT AND CYTOTOXIC POTENTIAL OF CALOTROPIS PROCERA (R. BR.) ROOTAbstract
This study evaluated the in vitro antioxidant and cytotoxic potential of methanolic extract of the root of Calotropis procera (R. BR.). The Antioxidant activity of the extract was investigated by the In-vitro Anti-Oxidant activity (DDPH Scavenging activity) assays. The IC50 of the Calotropis procera studied by the above mention method was found below 100 μg/ml which indicates the potent antioxidant activity of the plant. The extract of the root of Calotropis procera also demonstrated a strong cytotoxic activity against brine shrimp nauplii with an LC50 value of 2.931 μg/ml.
Md. Zakaria Faruki , Mithilesh Kumar Jha*, Md. Mofizur Rahman , M. B. Alam , M.E.H. Mazumder and Md. Sohel Rana
Lecturer, Department of Pharmacy, School of Health and Allied Sciences, Pokhara University, Lekhnath-12, Kaski, Nepal
05 April, 2011
10 June, 2011
09 July, 2011
01 August, 2011