IN VITRO ANTIOXIDANT AND FREE RADICAL SCAVENGING ACTIVITY OF STEM OF MUSSAENDA ERYTHROPHYLLAAbstract
Mussaenda erythrophylla is native to western tropical Africa, occasionally seen in gardens and parks as ornamental plant in India and belongs to Rubiaceae family. The present study was concentrated on the in vitro antioxidant methods like superoxide radical, hydroxyl radical, lipid peroxidation and DPPH radical methods. The ethylacetate and methanolic extracts of Mussaenda erythrophylla were subjected for the above methods. The results of anti oxidant activity revealed that, the ethylacetate extract has lower IC50 values than the methanolic extract of Mussaenda erythrophylla. The lower IC50 value indicates the higher free radical scavenging ability. So, the ethylacetate extract has better antioxidant activity than methanolic extract. The results were compared with the standard ascorbic acid. The plant contains phytosterols, triterpenoids, flavonoids, glycosides, saponins and tannins. These active constituents alone or in combination may be responsible for the observed antioxidant activity.
M Chinna Eswaraiah* and T Satyanarayana
Anurag Pharmacy College, Kodad, Nalgonda (Dt), University College of Pharmaceutical Sciences, Andhra University, Visakhapatnam, Andhra Pradesh, India
19 May, 2010
14 July, 2010
21 August, 2010
15 September, 2010