IN VITRO ANTIOXIDANT EFFICACY OF TERMINALIA BELLIRICA SEED EXTRACT AGAINST FREE RADICALSAbstract
In the present study Terminalia bellirica seeds, were evaluated for the In vitro anti-oxidant activity and phytochemical evaluation using different solvents such as methanol, ethylacetate, chloroform and aqueous. The in vitro antioxidant activity of Terminalia. bellirica is screened by standard antioxidant assays such as 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals, hydroxyl radicals and Total antioxidant activity by ABTS assay. The ethylacetate extract of T. bellirica seed extract was found to be relatively high activity (84±0.6) than other extracts. Similarly the ethyl acetate exhibits high antioxidant status in ABTS and hydroxyl scavenging assays. In comparison to other extracts the ethyl acetate and methanolic extract found significant and prominent antioxidant activity due to the presence of high phenolic and steroid content. Finally this study concludes that all the seed extracts of T. bellirica exhibiting high antioxidant potential with respect to dose depending manner.
L. A. A. Elizabeth*, G. Bupesh and R. Susshmitha
Department of Pharmacology, Sree Balaji Medical College and Hospital, Chromepet, Chennai, Tamil Nadu, India.
13 March, 2017
24 May, 2017
17 September, 2017
01 November, 2017