IN-VITRO ASSESSMENT, ISOLATION AND SPECTRAL ANALYSIS OF THE PETROLEUM ETHER EXTRACT OF PUMPKIN SEEDAbstract
Cucurbita Maxima, commonly known as pumpkin, which belongs to the family Cucurbitaceae, have numerous bio-active compounds such as polyphenols, dietary fibers, carotenoids, and minerals. This seed possesses anti-inflammatory and anti-oxidant properties and can be used in the neuro regenerative effects. In the present paper, an attempt has been made to reveal the phytochemical screening, anti-oxidant, anti-inflammatory activity and GC-MS spectral analysis of the isolated fatty acids compound of the plant Cucurbita maxima. From the anti-oxidant and anti-inflammatory activity of the petroleum ether extract showed good activity and proceeded for isolation; six fatty acid compounds were isolated from the seed Cucurbita maxima and analyzed using GC-MS and NMR. From the analysis, 10 compounds were identified by comparing their retention time and peak area with that of literature and interpretation of MS. The majority of phytoconstituents were 9-octadecenoic acid (Z), Oleic acid, 2-oxo-Cycloheptanevaleric acid and 14-Methyl-13-oxa-15-aza-dispirob [220.127.116.11] pentadec-14-ene. Hence this study helps in the screening of many bioactive components for the treatment of many diseases.
G. Neelamma *, S. H. Rasheed, K. Sulthana and P. Srilekha
Department of Pharmacognosy and Phytopharmacy, Srikrupa Institute of Pharmaceutical Sciences, Siddipet, Telangana, India.
01 January 2020
11 April 2020
15 April 2020
01 January 2021