IN VITRO EVALUATION OF ANTIMICROBIAL ACTIVITY OF MORINGA OLEIFERA AND MOMORDICA CHARANTIA SEEDS
AbstractThe aqueous and methanol extracts of the seeds of Moringa oleifera (Family: Moringaceae) and the seeds of Mormordica charantia (Family: Cucurbitaceae) were screened for their antimicrobial activity against three human pathogenic bacterial strains and three fungal strains by agar-well diffusion assay. The pattern of inhibition varied with the solvent used for extraction and the microorganisms tested. Among these extracts, methanol extract showed significant antimicrobial activity against all the six tested microbes. The most susceptible microorganism was Staphylococcus aureus which showed 8 mm and 7 mm zone of inhibition with methanol extract of M.oleifera and M.charantia respectively. M.oleifera methanol extract was significantly effective against the fungi C.albicans as comparable to the standard flucanozole. Preliminary phytochemical analysis of different extracts revealed the presence of flavonoids, terpenoids and tannins in M.oleifera methanol extract and the presence of alkaloids, glycosides and tannins in M.charantia methanol extract. These compounds may have contributed to their antimicrobial action
Article Information
50
1988-1993
477KB
1744
English
IJPSR
F. G. Shoba*, V.A. Babu, M. Parimala and J. Sathya
P.G. & Research Department of Zoology, Voorhees College, Vellore – 632001, Tamilnadu, India
gricildashoba@gmail.com
13 December, 2013
17 January, 2014
10 March, 2014
http://dx.doi.org/10.13040/IJPSR.0975-8232.5(5).1988-93
01, May 2014
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