IN VITRO EVALUATION OF ANTIOXIDANT AND ANTIMICROBIAL ACTIVITY OF SERIES OF NEW PYRAZOLE DERIVATIVES; A STUDY ON THE STRUCTURE-ACTIVITY RELATIONSHIPAbstract
In present study, a series of new synthesized condensed pyrazole derivatives 1a-f have evaluated in vitro for their antioxidant activity, reducing power ability, antibacterial activity against Gram-positive and Gram-negative organisms and antifungal activity against different organisms. Minimum inhibitory concentration against the bacterial and fungal strains was determined. The study provides the structural impact of the compounds for their biological activity.
G. Vasanth Kumar , M. Govindaraju , N. Renuka , G. Pavithra , B.N. Mylarappa and K. Ajay Kumar*
Associate Professor, Department of Chemistry, Yuvaraja’s College, University of Mysore 1, Mysore, India
11 August, 2012
22 September, 2012
24 November, 2012
01 December, 2012