IN-VITRO SCREENING OF EXTRACTS OF CENTELLA ASIATICA (LINN) URBAN FOR ANTIBACTERIAL PROPERTIESAbstract
Centella asiatica (Linn) Urban, a herb of immense medicinal properties, has been widely used by traditional healers in the treatment of skin diseases, mental fatigue, anxiety, rheumatism, eoilepsy and leprosy. In the present investigation, the antibacterial activity of ethanol, acetone and aqueous extracts of Centella asiatica were tested in-vitro against seven bacterial species viz. Staphylococcus aureus, Salmonella typhi, Salmonella paratyphi, Klebsiella sp., E. coli, Bacillus sp. and Pseudomonas sp. by well diffusion method. The ethanol extract inhibited the growth of Bacillus sp. and S. aureus, maximally (14 mm each), followed by that of E. coli (12 mm) and Klebsiella sp. (11 mm). The extract unaffected the growth of Salmonella typhi, Pseudomonas, and Salmonella paratyphi. The acetone extract inhibited the growth of Bacillus sp. (10 mm); the other six bacteria remained unaffected. Likewise, the aqueous extract also inhibited the growth of none of the test bacteria in this study.
Lincy Sara Varghese * and Krishna Suresh
Department of Botany, Bishop Kurialacherry College for Women, Amalagiri P.O., Kottayam, Kerala, India.
27 January 2022
02 April 2022
27 April 2022
01 September 2022