ISOLATION AND CHARACTERIZATION OF NATURAL PRODUCT COMPOUNDS FROM RHIZOMES OF CYPERUS ROTUNDUS LINN.Abstract
Background: Cyperus rotundus Linn. is a traditional medicinal plant appearing among Indian, Chinese and Japanese natural drugs, used for the treatment of spasms stomach disorder and also used as anti-inflammatory, antimalarial, hypotensive, antipyretic, anthelmintic, hepatoprotective agent. Rhizomes of C. rotundus have been used in ancient medicine in India for fever, dysentery, pruritis, pain, vomiting and various blood disorders. Objective: To isolate active Phytochemicals from rhizomes of title Plant. Materials and Methods: Petroleum ether extract of rhizomes was chromatograph over silica gel column and eluted with different solvent systems. Characterization of isolated compounds was done on the basis of spectral studies (IR, 1HNMR, 13CNMR, MS). Results: Ellagic acid (I), 6-hydroxy-3, 4-dimethyl coumarin (II), 6-methoxy-7, 8-methylenedioxy coumarin (III) and quercetin (IV) were isolated. Conclusion: Rhizomes of title plant are rich source of natural compounds and these compounds have very useful medicinal activities so present work gives a direction for future investigators to get some medicinally important drugs.
T. C. Sharma, A. K. Sharma *, S. K. Meena, M. P. Dobhal and M. C. Sharma
Department of Chemistry, Jagan Nath University, Jaipur, Rajasthan, India.
17 October, 2017
16 February, 2018
04 March, 2018
01 July, 2018