ISOLATION OF β-SITOSTEROL & STIGMASTEROL AS ACTIVE IMMUNOMODULATORY CONSTITUENTS FROM FRUITS OF SOLANUM XANTHOCARPUM (SOLANACEAE)Abstract
General phytochemical screening of the aqueous extract of fruits of Solanum xanthocarpum (Solanaceae) revealed the presence of steroids, terpenes, phenolic compounds, saponins, fatty acids, alkaloids. Fractionation of aqueous extract and activity guided isolation resulted in isolation of two white crystalline powder which were subjected to physical, chemical and spectral identification using IR, 1H‐NMR, 13C‐NMR and LC‐MS. On the basis of the spectral data analysis and chemical reactions, the compounds have been established as β-sitosterol and Stigmasterol.
S. Khanam* and R. Sultana
Department of Pharmacognosy, Al Ameen College of pharmacy, Hosur Road, Bangalore-560027, Karnataka, India
28 November, 2011
14 January, 2012
28 March, 2012
01 April, 2012