ISOLATION OF PENICILLIUM SP. AND ITS ANTAGONISTIC ACTIVITY AGAINST DERMATOPHYTES FROM VOLCANO SOIL OF BARATANG ISLAND, ANDAMANAbstract
Penicillium sp. was isolated from the mud volcano of Baratang Island, Andaman, were tested for the growth inhibition against four fungal species of dermatophytes viz., Epidermophyton flococususm, Microsprum gypseum, Tricophyton rubrum, Tricophyton mentagraphytes. Three different concentration of fungal suspension (10µl, 25 µl and50 µl) were tested using disc diffusion method. Penicillium sp. showed promising antidermatophytic activities against all four pathogens. Among the concentration tested maximum activity against M. gypseum (25mm) in the concentration of 50 µl and minimum activity expressed against E. flococusum (9mm) in the concentration of 10 µl. Further, the isolation and characterization of the novel anti-dermatophytic compound is in progress.
A. Dhinakaran*, M. Kalaiselvam, V. Sekar and G.V.B. Sethubathi
Centre of Advanced Study in Marine Biology, Faculty of Marine Sciences, Annamalai University, Parangipettai- 608 502, India
14 October, 2011
16 December, 2011
22 January, 2012