LCMS/MS QUANTITATION OF CATECHOLAMINES AND THEIR PREDECESSORS FROM PORTULACA OLERACEA AND GOMPHRENA GLOBOSAAbstract
The plants Portulaca oleracea and Gomphrena globosa belong to the order Caryophyllales, and their flowers are known to produce betalains. The biosynthesis of betalains involves various intermediate molecules such as catecholamines or biogenic amines. Catecholamines include dopamine, adrena-line (epinephrine), and noradrenaline (norepinephrine) and are normally believed to be released in response to stress. They are derived from the amino acid tyrosine, with L-DOPA being formed as an intermediate. Catecholamines and their predecessors (tyrosine and L-DOPA) have many medicinal applications and are used in the treatment of Parkinson’s disease, hypotension, low cardiac output, glaucoma, and allergic conditions like asthma, to name a few. These biogenic amines and their predecessors have been found in many plant families. Their presence has been reported in Portulaca oleracea and Gomphrena globosa. The current study focuses at the identification and quantification, by LCMS/MS, of the different catecholamines or their predecessors that are present in Portulaca oleracea and Gomphrena globosa.
M. Sandhya *, P. Jessy and D. Shailesh
Department of Botany, Ramnarain Ruia Autonomous College, Matunga, Mumbai, Maharashtra, India.
30 November 2020
14 March 2021
25 May 2021
01 November 2021