LEISHMANICIDAL EFFECTS OF OLEA EUROPAEA LINN. EXTRACT AGAINST PROMASTIGOTE AND AMASTIGOTE FORMS OF SOME LEISHMANIA SPP
AbstractHere, we evaluated the in vitro antileishmanial activities of Olea europaea linn. leave extract (OLE) on some Leishmania spp. OLE (0–160 ?g/mL) was considered against promastigote and intracellular amastigote forms of L. tropica (MHOM/IR/2002/Mash2) and L. major (MRHO/IR/75/ER) using MTT assay and in a macrophage model, respectively. The obtained findings demonstrated that OLE significantly (?<0.05) inhibited the growth rate of promastigote and amastigotes as a dose and time dependent response. To conclude, the current investigation exhibited effective antileishmanial activity of OLE.
Article Information
46
4869-4874
741
1074
English
IJPSR
F. Kheirandish, B. Delfan, S. Fallahi, M. H. Kayedi, M. Rashidipour and S. Jahanbakhsh*
Bam University of Medical Sciences, Bam, Iran.
sarehjahanbakhsh@gmail.com
15 March, 2017
24 May, 2017
17 September, 2017
10.13040/IJPSR.0975-8232.8(11).4869-74
01 November, 2017