MEDICINAL PLANTS AND PHYTOCHEMICALS AGAINST PSEUDOMONAS AERUGINOSA QUORUM SENSING
AbstractMedicinal plants are significantly used in the cure of various ailments from ancient times. Literature suggests that traditional medicinal plants from Fabaceae, Lamiaceae, Myrtaceae, and Anacardiaceae, Combretaceae family are widely studied, and they potentially inhibit quorum sensing, a bacterial communication mechanism that leads to the pathogenesis. Plants such as Anogeissus leiocarpus, Brassia oleraceae, Camellia nitidissima, Cassia alata, Laserpitium ochridanum, Neppenthes alata, Parkia javanica, Pistacia atlantica, Plantago asiatica, Psidium guajava, Quercus infectoria, Terminallia bellerica, Terminallia catappa, are reported to be effective in quorum sensing inhibition. Plant extracts containing phytochemicals such as quercetin, kaempferol, myricetin, baicalin, cassipourol, 6-gingerol and eugenol were reported to be potential inhibitors of Pseudomonas aeruginosa quorum sensing. Bioactive principles from medicinal plants with anti-quorum sensing properties are remarkable substitutes for synthetic antibacterial drugs, especially in the era of multi-drug resistant (MDR) pathogens. The anti-quorum sensing activity of medicinal plants against the Pseudomonas aeruginosa, a gram-negative MDR bacterium, is reviewed for the period from 1997 to 2019.
Article Information
3
4749-4773
1085
1174
English
IJPSR
J. Murugesan and S. K. Sripathi *
Department of Chemistry, Avinashilingam Institute for Home Science and Higher Education for Women Coimbatore, Tamil Nadu, India.
adusks2@gmail.com
14 October 2019
23 March 2020
27 March 2020
10.13040/IJPSR.0975-8232.11(10).4749-73
01 October 2020