MEDICINAL SIGNIFICANCE OF LOVASTATIN
AbstractLovastatin is a naturally occurring drug of statin family used for lowering cholesterol. It is found that it can be useful for treatment or management of multiple diseases and has immense medicinal significance. On one side, this drug is used to induce apoptosis in various cancer cells, while other reports indicate that it also promotes cell survival to alleviate certain disease conditions. Antiviral role of lovastatin has also been reported. So, lovastatin, if recommended for any therapy, first requires thorough study as well as experimentations both in-vitro and in-vivo. Current review is systematic, based on search from PubMed by entering key words “Lovastatin cancer, Lovastatin apoptosis and Lovastatin survival” with filter for seven years (2008-2014) data only. It is concluded from the study that Lovastatin has multidirectional role and may be helpful in cancer cells apoptosis as well as survival of certain types of cells. It may be used as anti-viral agent also
Article Information
4
971-977
553
1987
English
Ijpsr
N. Wajid *, S. S. Anwar, F. Ali, M. Zahoor, N. Hamid, M. M. Aslam and A. Ali
Institute of Molecular Biology and Biotechnology, The University of Lahore , Lahore, Pakistan
Nadia.wajid@imbb.uol.edu.pk
19 June, 2014
15 September, 2014
16 November, 2014
http://dx.doi.org/10.13040/IJPSR.0975-8232.6(3).971-77
01 March, 2015
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