MEMBRANE STABILIZING ACTIVITY AND ANTIOXIDANT EFFECT OF SIDA CORDATA (BURM F.) BIOSS AND RHODODENDRON ARBOREUM SM. LEAVESAbstract
Purpose: To investigate membrane stabilizing activity and antioxidant activity off different extracts of leaves of Sida cordata and Rhododendron arboreum.
Methods: Preliminary phytochemical analysis of different extracts of leaves of Sida cordata and Rhododendron arboreum were performed for presence of phytoconstituents. In vitro membrane stabilizing activity was done by using RBC membrane stabilising activity and antioxidant activity was done by using DPPH method.
Results: Preliminary phytochemical analysis showed that methanol extract are very rich in phytoconstituents as they showed the presence of alkaloid, carbohydrate, glycosides, proteins and amino acid, Phenolic compounds. All extract are investigated for their in vitro membrane stabilizing activity and antioxidant effect. Methanol and acetone extract of Sida cordata and Rhododendron arboreum showed maximum effect in comparison with other extracts.
Conclusion: From the above study it could be concluded that the leaves of Sida cordata and Rhododendron arboreum showed protective effect on inflammation and oxidant.
Deepak Kumar*, Shefali Arora , Manoj Kumar , Manoj Kumar Thakur and Abhay Pratap Singh
Department of Pharmaceutical Chemistry, Dolphin (PG) Institute of Biomedical and Natural Sciences 1, Dehradun, Uttarakhand, India
05 August, 2013
11 September, 2013
17 December, 2013
01 January, 2014