MODERN ENCROACHMENT AND PROVOCATION IN NASAL DRUG DELIVERY SYSTEMAbstract
Nasal drug delivery has occupied an important place in the field of drug delivery technology. Transmucosal nasal delivery is a promising drug delivery option where common drug administration’s (e.g. intravenous, intramuscular, and oral) are inapplicable. This route is also advisable for drugs undergoing extensive first pass effect. The physiology of the nose presents obstacles, but offers a promising route for non-invasive systemic delivery of numerous therapies and debatably drug delivery route to the brain. Nasal route is easily accessible for self-administration without the help of health professionals and no needle stick hazards are associated with nasal administration. To overcome these problems in nasal drug delivery, deep understanding and study of the various factors affecting nasal delivery is muust. Thus present review focuses on various aspects of nasal drug delivery with special emphasis on various formulations available, obstacles, advancement and future prospects in nasal drug delivery.
P.R. Patil*, V.K. Salve, R.U. Thorat, P.K. Puranik and S.S. Khadabadi
Department of Pharmaceutics, Government College of Pharmacy, Opposite Govt. Polytechnic, Osmanpura, Aurangabad 431 005, Maharashtra, India
08 March, 2013
19 April, 2013
21 June, 2013
01 July, 2013