MORINGA OLEIFERA (MO) SEED CATALYZED THE SYNTHESIS OF BENZIMIDAZOLE DERIVATIVESAbstract
A simple, one-pot, and efficient method for the synthesis of benzimidazole derivatives via the condensation of o-phenylenediamine and substituted aromatic aldehydes in the presence of Moringa oleifera (MO) seed extract acts as a biocatalyst under microwave irradiation. The method provides several advantages such as simple operation, clean reaction ways, and high to the excellent yield of product. The aqueous extract of Moringa oleifera (MO) seed as a green catalyst corresponds to an excellent yield for the synthesis of 2, 4, 5-trisubstituted imidazole derivatives under microwave irradiation method as a greener heating technique and one-pot multicomponent reaction acts as a green routine. All synthesized compounds were characterized by spectroscopic techniques such as FT-IR, 1H-NMR, 13C-NMR and LC-MS analysis.
Shahabaj M. Bagwan * and Mohamad Asif
Maulana Azad Research Center, Maulana Azad College, Aurangabad, Maharashtra, India.
11 January 2022
31 March 2022
26 April 2022
01 September 2022