NANOSPONGES – NOVEL EMERGING DRUG DELIVERY SYSTEM: A REVIEW
AbstractThe advent of nanotechnology lead to invention of many dosage forms. Effective targeted drug delivery systems have been a dream for a long time, due to several major drawbacks, a practical approach has been developed for the formation of discrete functionalized particles, which have been termed as ‘Nanosponge’. The development of new colloidal carrier called Nanosponges has the potential to solve these problems. Nanosponge is a novel and emerging technology it can precisely control the release rates of controlled drug delivery for topical use. The invention of Nanosponges has become a significant step toward overcoming these problems. Nanosponges are tiny sponges with a size of about a virus, which can be filled with a wide variety of drugs. These tiny sponges can circulate around the body until they encounter the specific target site and stick on the surface and begin to release the drug in a controlled and predictable manner. Because the drug can be released at the specific target site instead of circulating throughout the body it will be more effective for a particular given dosage. Another important character of these sponges is their aqueous solubility; this allows the use of these systems effectively for drugs with poor solubility
Article Information
4
529-540
638KB
4490
English
Ijpsr
Shastrulagari Shivani * and Kranthi Kumar Poladi
Samskruthi College of Pharmacy, Ghatkesar, Ranga Reddy- Dist-501301, Telangana, India
Pharma.shivani45@gmail.com
09 June, 2014
08 August, 2014
13 October, 2014
http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).529-40
01 February, 2015