NANOSTRUCTURED LIPID CARRIERS: A NOVEL TARGETED DRUG DELIVERY SYSTEMAbstract
Over the previous decade, several drug delivery systems have come into view, and an alluring part of this is the advancement of nanoparticle systems. Lipid drug delivery systems has considered as one of the emerging technologies and obtained attention due to features like biocompatibility, lipophilic characteristics. Among nanoparticle Nanostructured lipid carriers (NLC) have numerous advantages than emulsions, liposomes, microparticles, and solid lipid nanoparticles (SLN). NLC is a second-generation nanoparticulate system and has solid nature at ambient temperature. It comprises mainly of solid lipid, liquid lipid, surfactants, and water. It is approved by regulatory authorities to use as drug delivery systems. Due to ease in formulation, the practicability of large scale production, biocom-patibility of components used, non-toxicity, and improved targeting efficiency, NLC has a number of applications in the cosmetic industry and pharmaceutical industry. This review highlights its types, the various formulation techniques, and evaluation techniques. The review also provides an application of NLC as a targeted delivery system.
D. Patil *, S. Pattewar, S. Palival, G. Patil and S. Sharma
Department of Pharmacy, Banasthali Vidyapith, Banasthali, Rajasthan, India.
23 December 2019
04 February 2020
11 March 2020
01 October 2020