NATURAL GELLING AGENTS POLYMER IN PHARMACEUTICAL PREPARATIONAbstract
Pharmaceutical preparation mostly contains active ingredients and excipients. The function of excipients to improve the physicochemical properties of pharmaceutical manufacturing products. In pharmaceutical preparation, polymer plays a key role act as excipients in any dosage formulation development. Polymers are derived from the source of natural and synthetic. The polymer should have basic properties such as stable, biocompatible, non-toxic, economical, biodegradable, and hydrophilic and influence the release of the drug. For designing any pharmaceutical dosage form, the selection of polymer play a key role because due to polymer diversity. Natural polymers help in the improvement and control of the pharmacokinetics of the drug. In recent times, pharmaceutical manufacturing companies use a natural polymer to resolve the problem of side effects and drug release in sustained release formulation. The polymers which isolate naturally are mostly polysaccharides. Here in this review discussion of natural polymer source, solubility, chemical nature, and pharmaceutical application for novel drug formulation.
Muhammad Masood Ahmad and Syed Nasir Abbas Bukhari
Department of Pharmaceutics, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia.
20 October 2020
03 June 2021
13 June 2021
01 December 2021