NIOSOMES: A ROLE IN TARGETED DRUG DELIVERY SYSTEMAbstract
Niosomes are non-ionic surfactant vesicles inclosing an aqueous phase and a wide range of molecules could be encapsulated within aqueous spaces of lipid membrane vesicles. They are microscopic lamellar structures formed on the admixture of a non-ionic surfactant, cholesterol and phosphate with subsequent hydration in aqueous media. Niosomes belongs to novel drug delivery system which offers a large number of advantages over other conventional and vesicular delivery systems. Namely they are the targeted drug delivery system which showing reduction of dose, stability and compatibility of non-ionic surfactants, easy modification, delayed clearance, suitability for a wide range of Active Pharmaceutical Agents.
Department of Pharmaceutics, Jaipur College of Pharmacy, ISI-15, RIICO Institutional Area, Sitapura, Tonk Road, Jaipur (Rajasthan)-302022, Rajasthan, India
07 October, 2012
29 November, 2012
18 January, 2013
01 February, 2013