OINTMENT OF METHANOLIC EXTRACT OF FICUS RELIGIOSA: A TRADITIONAL APPROACH IN WOUND HEALING IN RATSAbstract
The methanolic extract (ME) of leaves of Ficus religiosa (Family: Moraceae) was evaluated for their wound healing activity in rats. It was carried out in rats by employing excision wound models following topical application. The qualitative preliminary phytochemical analysis of ME indicated the presence of tannins, triterpenoids, alkaloids and steroids. All healthy animals of either sex were grouped into four groups and each group contains six rats. The rats of ointment (5 and 10 %w/w) of ME treated were compared to povidone-iodine ointment treated as a standard. The results of present work revealed that the 10%w/w ointment of ME of Ficus religiosa treated wounds showed significant reduction of wound contraction area as compared to control and indicated rapid epithelialisation.
Reena Gupta* and Jitendra Gupta
Institute of Pharmaceutical Research, GLA University, Chaumuha, Mathura, Uttar Pradesh, India
06 June, 2016
07 July, 2016
09 July, 2016
01 December, 2016