ORAL AND SYSTEMIC SIDE EFFECTS OF CANCER CHEMOTHERAPY AND EFFECT OF BENZYDAMINE MOUTHWASH IN ORAL MUCOSITISAbstract
Aim: To check the effectiveness of 0.15% Benzydamine hydrochloride on oral mucositis secondary to cancer chemotherapy
Methods: In the past few years, multiple cases were referred to our department for the management of oral manifestations of cancer chemotherapy for various malignancies. Out of these patients, we selected 5 patients and used a simple, inexpensive treatment modality in consideration with patient’s affordability and convenience. They were prescribed 0.15% Benzydamine hydrochloride oral rinse (Tantum) for the relief of oral discomfort.
Results: Significant reduction in oral mucositis and discomfort was observed after a week. The treatment was continued for 3 weeks till complete disappearance of oral ulcers.
Conclusion: Benzydamine oral rinse is simple, effective, safe, inexpensive and well tolerated therapeutic modality for prophylactic and palliative treatment of chemotherapy-induced oral mucositis. It holds a special significance in the developing countries such as India for the lower socioeconomic strata.
Anagha Shete* , Samapika Routray , Mahesh S. Chavan , Nikhil N. Diwan and Mrinal Shete
MDS, Senior Lecturer, Department of Oral Medicine and Radiology, Dr. D.Y. Patil Dental College and Hospital, Pimpri, Pune- 411018, Maharashtra, India
27 May, 2012
29 June, 2012
23 August, 2012
01 September, 2012