PAIN AND INFLAMMATION: A REVIEWAbstract
This article enlightens physiological components of pain and inflammation. The objective is to study pain, inflammation and their pathophysiology. It is one of the common and one of the most difficult problems to diagnose and is generally fund in common people. Pain is a complex experience which includes psychological and behavior components and results from trauma, diseases, surgical interventions. Pain is an unpleasant sensation and an emotional experience associated with a real or potential damage to tissue, or equivalent of such damage. Inflammation is a process which arises due to tissue damage causing dilation of venules, increase in vascular permeability, and infiltration of histamine, cytokines and other inflammatory components. Inflammation occurs due to the stress responses and is an integral part of it. The paper is related with the pathological changes in pain, inflammation, components producing the changes. Different mediators like IL, PG, PAF, LT, cytokines are producing inflammation and leading to pain.
Brij Mohan Singh *, Gaurav Negi , Praveen Bhole , Manju Jaiprakash
Drug Regulatory Affairs, Axa Parenterals Ltd. , Roorkee, Uttarakhand, India
03 August, 2012
12 October, 2012
29 November, 2012
01 December, 2012