PHARMACEUTICAL VALIDATION & PROCESS CONCEPTUALISATION OF ANCIENT INDIAN CALCIUM PREPARATION: SHANKHA BHASMAAbstract
In the present study, the pharmaceutical and therapeutic dimensions of Shankha Bhasma (Classical Ayurvedic marine medicine) is explored as a substitute for calcium supplements available in the market. Shankha Bhasma was prepared & standardized by Ayurvedic pharmaceutical procedure accordingly in Rasa Tarangini (a classical 20th-century book on Ayurvedic pharmaceutical medicine). Conch shell (Shankha) was subjected to bio-fomentation (Swedana) in a precise heating container (Dolayantra) containing lemon juice for 12 h. Further, triturated with Aloe vera juice (Kumari Swarasa) for bio-impregnation (Bhavana) and subjected to the controlled quantum of heat (Marana) in the sealed earthen saucer at 700 °C for 2 h, till all the classical and contemporary quality parameters about bio-metallic medicinal powder (Bhasma) was assured. On completion, average weight loss was 17-21%. The final product obtained was calcite form of CaCO3 and calcium oxide hydrate (CaO.H2O). This paper explores scientific evidence of ancient Ayurvedic pharmaceutical procedures in terms of bio-fomentation, bio-impregnation, transfer mechanism of quantum of heat along with the principles of fluid mechanics & thermodynamics.
V. Meena *, S. Bhushan and A. Chaudhary
Department of Rasa Shastra & Bhaishajya Kalpana, Faculty of Ayurveda, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
17 January 2019
20 April 2019
13 June 2019
01 October 2019