PHARMACOGNOSTIC, PHYTOCHEMICAL AND ANTIOXIDANT ACTIVITY STUDIES ON CORDIA OBLIQUA WILLD. LEAFAbstract
Cordia obliqua Willd. (Clammy Cherry) belongs to genus Cordia and family Boraginaceae. It possesses a number of traditionally mentioned medicinal activities like purgative, diuretic, antipyretic, anthelmintic, analgesic and hepatoprotective. The present work is related with Pharmacognostic, Phytochemical and antioxidant study of Cordia obliqua leaf. Under Pharmacognostic study various parameters like macroscopic, microscopic and physiochemical parameters were studied as per WHO guidelines. This work will be helpful in authentication of Cordia obliqua Willd. plant. After this successive soxhlet extraction was performed for leaf powder with various solvents in increasing order of polarity like Hexane, Chloroform, Methanol and water. These extracts were used to study presence of various chemical constituents as well as to determine amount of total Phenol and Flavonoids content. Further antioxidant activity study was performed with help of DPPH and H2O2 radical scavenging methods. The leaf methanol extract was found to have maximum amount of Phenols and Flavonoids. In antioxidant activity study, again the results with methanol extract were found better and comparable with standard and it may be due to presence of more amounts of Phenols and Flavonoids. Finally it was concluded that the leaf methanol extract is a good antioxidant and it may also be helpful in other biological activity study.
R. Gupta * and G. D. Gupta
Department of Pharmacognosy, ASBASJSM College of Pharmacy, Bela (Ropar) , affiliated to I. K. Gujral Punjab Technical University, Jallandhar, Punjab, India
14 June, 2016
12 July, 2016
02 August, 2016
01 November, 2016