PHARMACOGNOSTICAL, PHYTOCHEMICAL AND PHARMACOLOGICAL INVESTIGATION ON LEAVES OF TRIDAX PROCUMBENS LINN.Abstract
The study is aimed at development of physicochemical parameters and to investigate the active principle present in Tridax procumbens Linn. Tridax procumbens Linn. (Asteraceae) commonly known as Coat Buttons is an important plant used against various disorders in indigenous system of medicine such as Wound-Healing, Hepatoprotective, Anti-Inflammatory, Anti-diabetic and Immunomodulatory activities. However its functional properties and the underlying mechanism of action have not been clearly defined, the present study was undertaken to evaluate anthelmintic activity of methanol extract of leaves of Tridax procumbens L. against Pheretima posthuma (earthworm). Various concentrations (10, 20, 30mg/ml) of methanolic extract were evaluated in the bioassay involving determination of time of paralysis (P) and time of death (D) of the worms. Albendazole was used as standard anthelmintic drug and distilled water was used as control. The results of present study indicated that the methanolic extract of leaves of Tridax procumbens showes significantly dose depending pharmacological activity.
Sangeeta Kumari , Swati Jain , Rita Pal, Sumitra Nain* and Sarvesh Paliwal
Department of Pharmacy, Banasthali University, Banasthali Tonk- 304 022, Rajasthan, India
21 September, 2012
10 January, 2013
29 January, 2013
01 February, 2013