PHARMACOGNOSTICAL STANDARDIZATION OF AYURVEDIC HEPATOPROTECTIVE DRUG PHALATRIKADI KVATHAAbstract
To investigate an Ayurvedic compound formulation Phalatrikadi Kvatha (PTK) having seven plant origin drugs for quality control and standardization. This compound formulation is mentioned in Ayurvedic classics for the treatment of Kamala ~ hepatic disorders. Macroscopy, qualitative phytochemical analysis, extractive values in ethanol and water and thin layer chromatography (TLC) of the formulation was done. Physicochemical parameters include loss on drying, total ash, acid insoluble ash, sulphated ash, alcohol soluble extractive, water soluble extractive and preliminary phytochemical screening of various solvent extract (hexane, chloroform, ethyl acetate, methanol and aqueous). Phytoconstituents such as Tannins, Saponin, Flavonoids, and Steroids were found to be present. Further TLC of Alcoholic extract of Phalatrikadi Kvatha (PTK) was done for proper identification. The qualitative phytochemical and pharmacognostic study of the drug is helpful in sample identification, quality and purity standards of the plant materials. The result of the present study can serves as valuable source of information and provides suitable standards for identification of PTK formulation for future investigation and its application.
Nirmal Kumar* and Shivani Ghildiyal
Departments of Dravyaguna, Faculty of Ayurveda, Institute of Medical Sciences, Banaras Hindu University, Varanasi–221005, Uttar Pradesh, India
21 April, 2013
10 October, 2013
23 September, 2013
01 January, 2014