PHARMACOLOGICAL STUDY OF THE PELTOPHORUM PTEROCARPUM FLOWERAbstract
The present study was designed to investigate in vivo analgesic and cytotoxicity as well as in vitro antibacterial activities of the methanol: ethylacetate (1: 9) extract of the flowers of Peltophorum pterocarpum. Analgesic activity was assayed by acetic acid induced assay method wherein the extract showed moderate activity in a dose dependent manner. In respect of in vivo cytotoxicity, the flower extract of Peltophorum pterocarpum showed moderate activity with 30% cell growth inhibition against Ehrlich Ascites Carcinoma (EAC) cells at a dose of 50mg/kg. Moreover, Antibacterial test were done against five Gram-positive and four Gram-negative bacteria. Flower extract was active against all tested microbial species except Staphylococcus aureus and the zone of inhibition range was found to be 12±0.32 to 18±0.11 mm.
M. Saiful Islam , Ronok Zahan , M. Badrul Alam , Marufa Naznin , M. A. Mosaddik , M. Ekramul Haque*
PhD, Department of Pharmacy, University of Rajshahi, Rajshahi - 6205, Bangladesh
02 May, 2011
21 August, 2011
23 August, 2011
01 September, 2011