PHENOLIC ACIDS AND FREE RADICAL SCAVENGING ACTIVITY OF ALCHEMILLA JUMRUKCZALICA PAWLAbstract
Comparative study of free radical scavenging activity and phenolic acid content of Bulgarian endemic Alchemilla jumrukczalica and the commercial herbal – Alchemilla vulgaris complex was carried.The methanol extracts of studied samples showed significant antiradical activity. The concentration of the extracts needed for 50% inhibition of DPPH was found to be 12,09 µg/ml and 19,62 µg/ml for A. jumrukczalica and A. vulgaris complex, respectively.Ten free and seventeen bonded phenolic acids were identified and quantified by performed of gas chromatography mass-spectrometry (GC-MS). Gentisic, protocatechuic, salicylicand trans-cinnamic acids were represented in the greatest quantityamong the identified phenolic acids. This is the first detailed analysis on qualitative and quantitative composition of phenolic acids inAlchemilla species.
M. Nikolova*, I. Dincheva , A. Vitkova and I. Badjakov
Institute of Biodiversity and Ecosystem Research, 23, Acad.G. Bonchev St., 1113 Sofia, Bulgaria
28 October, 2011
14 December, 2011
23 February, 2012