PHYTOCHEMICAL EVALUATION OF CASSIA AURICULATA USING ANALYTICAL STUDIESAbstract
Medicinal plants, herbs, spices, and herbal remedies are integral components of the alternative system of medicine since while’s ancient Cassia auriculata Linn is a potential folklore medicinal plant (Caesalpiniaceae) used for Ayurveda and Siddha systems of medicine. Plants contain a wide variety of phytochemical constituents, which are secondary metabolites and are used either directly or indirectly in the pharmaceutical industry. For centuries, man has effectively used various components of plants or their extracts for the treatment of many diseases. The aim of the study was to investigate the phytochemical compounds of Cassia auriculata and GC-MS analysis. The presence of phytochemical compounds was screened by a qualitative method using gas chromatography and mass spectroscopy (GC-MS). An aqueous and ethyl acetate extract obtained were subjected to GC-MS for the determination of bioactive volatile compounds. GC-MS analysis was carried out using claries 680 GC with clarus 600 (EI) MS. The GC-MS analysis of the aqueous and ethyl acetate extract revealed the presence of 26 bioactive compounds with valuable biological activities. The major chemical constituents were ethyl – 1 – thio – beta.- d-glucopyranoside (39.52%), (14.97%), tritetracontane (13.66%), hexatriacontane (11.19%), tetratetracontane (10.78%), neopentane-1,1-dioldiacetate(9.37%),1,6;3,4-dianhydro-2-deoxy-.beta.-d-lyxo-hexopyranose (6.62%). The presence of various bioactive compounds in C. auricular taproved the pharmaceutical importance. It can be concluded that the plant investigation has opened up a new perspective in pharmaceutical research and plants can be used for the development of potential, novel antioxidant agents for the treatment of many diseases.
V. J. J. Jancy *, V. K. Kalaichelvan and N. Balakrishnan
Department of Pharmacology, S. A. Raja Pharmacy College, Vadakkankulam, Tamil Nadu, India.
11 June 2020
22 October 2020
20 May 2021
01 June 2021