PHYTOCHEMICAL SCREENING AND ANTIOXIDANT ACTIVITY OF LEUCAS ASPERAAbstract
The purpose of the current work was to conduct phytochemical screening and antioxidant activity of different extracts of Leucas aspera. The dried powder of the whole plant was extracted with n-hexane, ethyl acetate and ethanol which were subjected to various chemical tests to ascertain the main constituents of the plant. The results revealed the presence of significant amounts of alkaloids, glycosides, tannins and flavonoids in ethanol extract while the other two extracts contain moderate amount of the chemical constituents. Our results indicate the presence of phytochemicals in the order of ethanol > ethyl acetate > n-hexane extract. Antioxidant activity of these extracts were performed by using DPPH free radical scavenging assay, total anti-oxidant capacity and the total phenol capacity where ascorbic acid (for DPPH scavenging and total anti-oxidant) and gallic acid (for total phenol) were used as standards. The results showed that the ethanol extract possesses more anti-oxidant activity than ethyl acetate and n-hexane extracts.
B. K. Das*, B. Das, F. K. Arpita, M. A. Morshed, A. Uddin, R. Bhattacherjee and J.M.A. Hannan
Department of Pharmacy, North South University, Bashundhara, Dhaka-1229, Bangladesh
30 March, 2011
05 May, 2011
25 June, 2011
01 July, 2011