PHYTOCHEMICAL SCREENING AND GUT MOTILITY ACTIVITY OF ETHANOLIC EXTRACT OF WHOLE PLANT OF SCUTIA MYRTINA KURZ.Abstract
Phytochemical and Gut motility activity of Ethanolic Extract of whole plant of Scutia Myrtina Kurz collected from Kolli Hills, Tamil Nadu was studied. Phytochemical studies revealed the presence of Alkaloids, Glycosides (Anthraquinone), Flavonoids and Tannins. For Gut Motility activity Extracts in concentration of 200mg/Kg and 400mg/Kg were studied in three animal models in comparison to Caster Oil and Glaxenna; (a) Gut motility activity in isolated Rat Intestine, (b) Propulsive Gut motility in mice & (c) Laxative activity in Mice. The Gut motility activity was assessed by different parameters depending on respective animal models. Caster Oil and Glaxenna were used as Standard drugs depending on the animal models. Gut motility in the test drug treated animals were found to be significant in all the models. Anthraquinone Glycosides present in the drug is probably responsible for the Gut motility activity.
N Goutam*, R Goutam, S Jain, S Deb Roy, K K Nayak, G Tomar and D N Sharma
Abhilashi College of Pharmacy, Ner Chowk, Dist: Mandi, (HP), India
24 April, 2010
14 June, 2010
02 August, 2010
15 August, 2010