PHYTOCHEMICAL SCREENING AND IN VITRO ANTIMICROBIAL INVESTIGATION OF THE METHANOLIC EXTRACT OF CENTELLA ASIATICA LEAVESAbstract
The methanol extract of Centella asiatica (Family:Umbelliferae) was studied for its phytochemical and pharmacological Activities. This study of the extracts indicates the presence ofReducing Sugar Tannins, Alkaloids, Sapponins and.The pharmacological study include Antimicrobial activities.The extract of the plant showed activity against a wide a variety of microorganism’s .All the activities were compared by measuring the zone of inhibition with the standard antibiotic. Based on the findings of Antimicrobial activity, we can say that the plant may contain novel compounds that possess potent anti-mutagenic activity and anti-oxidative activity. The obtained results support for the uses of this plant as traditional medicine. Infectious diseases are the second leading cause of death worldwide. Treatment of infections continues to be problematic in modern time because of the severe side effects of some drugs and the growing resistance to antimicrobial agents. The activities observed could be attributed to the presence of some of the phytochemicals detected which have been associated with antibacterial activity.
Rishikesh*, Md. Mofizur Rahman , S.M. Siddiqul Islam and Md. Moshfiqur Rahman
B. Pharm, MS. Pharm. Tech., Department of Pharmacy, Bangladesh University, Dhaka-1207, Bangladesh
18 May, 2012
27 July, 2012
27 August, 2012
01 September, 2012